Question: What Is Theophylline Chemically Similar To?

Is theophylline a metabolite of caffeine?

Theophylline (1,3-dimethylxanthine) has not been reported to be a metabolite in bacterial degradation of caffeine.

Subsequent N demethylation of theobromine or paraxanthine to xanthine is via 7-methyxanthine..

Why is theophylline not used?

With that said, theophylline may cause a worsening of certain medical conditions and may need to be avoided if you have: Cardiac arrhythmia (irregular heartbeat) Epilepsy or other seizure disorders.

Does coffee contain methylxanthine?

Linked to three of the most consumed beverages (coffee, tea, and cacao) are the most popular methylxanthines: caffeine, theophylline, and theobromine (Table 1). Caffeine is the most abundant methylxanthine in coffee, its level being smaller in chocolate than in coffee.

Is Aminophylline an antibiotic?

Aminophylline is a bronchodilator that is used with other medications to treat sudden worsening of the symptoms of asthma, bronchitis, or emphysema. Aminophylline may also be used for purposes not listed in this medication guide.

What foods contain theophylline?

Theophylline is found in black tea and to a lesser extent in green coffee, cocoa cotyledon and dried mate.

Is there a substitute for theophylline?

Abstract: Doxofylline, which differs from theophylline in containing the dioxalane group at position 7, has comparable efficacy to theophylline in the treatment of respiratory diseases, but with an improved tolerability profile and a favorable risk-to-benefit ratio.

Are theophylline and aminophylline the same?

Aminophylline is a compound of the bronchodilator theophylline with ethylenediamine in 2:1 ratio. The ethylenediamine improves solubility, and the aminophylline is usually found as a dihydrate. Aminophylline is less potent and shorter-acting than theophylline.

Is theophylline discontinued?

Reason for the Shortage Major has discontinued theophylline extended-release tablets. Teva has had theophylline extended-release tablets temporarily unavailable for several years. Theophylline 24-hour extended-release presentations are available from Mylan, Rhodes, and Endo Pharmaceuticals.

Does green tea contain theophylline?

Black tea, green tea, and oolong tea are all made from the same plant but are prepared using different processing methods. Green tea extract contains polyphenols. … Other significant parts of tea include caffeine, theobromine, and theophylline. The polyphenols of green tea are strong antioxidants.

What is the brand name for aminophylline?

Theophylline is available under the following different brand names: Theo 24, Theochron, Elixophyllin, aminophylline, and Uniphyl.

What is aminophylline chemically similar to?

Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Similar to other theophyllines, aminophylline is indicated for the treatment of lung diseases such as asthma, chronic bronchitis, and COPD.

What are the side effects of theophylline?

Nausea/vomiting, stomach/abdominal pain, headache, trouble sleeping, diarrhea, irritability, restlessness, nervousness, shaking, or increased urination may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

What is theophylline used for?

Theophylline is used to prevent and treat wheezing, shortness of breath, and chest tightness caused by asthma, chronic bronchitis, emphysema, and other lung diseases. It relaxes and opens air passages in the lungs, making it easier to breathe.

Does coffee interact with theophylline?

theophylline caffeine Avoid drinks or foods that contain caffeine, such as coffee, tea, cola, and chocolate. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs.

What is the mechanism of action of theophylline?

Mechanism of Action: Theophylline has two distinct actions in the airways of patients with reversible obstruction; smooth muscle relaxation (i.e., bronchodilation) and suppression of the response of the airways to stimuli (i.e., non-bronchodilator prophylactic effects).