Question: Has Theophylline Been Discontinued?

Is theophylline still used?

Theophylline is still one of the most widely prescribed drugs for the treatment of asthma and chronic obstructive pulmonary disease (COPD) worldwide, because it is inexpensive and widely available..

Does theophylline increase heart rate?

Heart rate was higher in the theophylline group than in the control group. Both pacemaker therapy and theophylline improved symptom scores after 3 months of treatment; however, a similar improvement was observed in the control group.

Does theophylline cause weight loss?

Common side effects of Theo-24 include mild nausea, loss of appetite, stomach pain, diarrhea, upset stomach, weight loss, restlessness, tremor, sleep problems (insomnia), headache, lightheadedness, dizziness, sweating, restlessness, nervousness, or irritability.

Does theophylline raise blood sugar?

high blood sugar –increased thirst, increased urination, dry mouth, fruity breath odor.

Does coffee contain methylxanthine?

Linked to three of the most consumed beverages (coffee, tea, and cacao) are the most popular methylxanthines: caffeine, theophylline, and theobromine (Table 1). Caffeine is the most abundant methylxanthine in coffee, its level being smaller in chocolate than in coffee.

What are the physicochemical properties of theophylline?

Theophylline is a dimethylxanthine having the two methyl groups located at positions 1 and 3. It is structurally similar to caffeine and is found in green and black tea. It has a role as a vasodilator agent, a bronchodilator agent, a muscle relaxant, an EC 3.1. 4.

What is the normal theophylline level?

Therapeutic serum levels of theophylline are between 10 to 20 mcg/ml. Most adults achieve these concentrations with daily slow-release oral theophylline preparations, 200-400 mg (approximately 10 mg/Kg) twice a day.

Where can you find theophylline?

Theophylline is naturally found in cocoa beans. Amounts as high as 3.7 mg/g have been reported in Criollo cocoa beans. Trace amounts of theophylline are also found in brewed tea, although brewed tea provides only about 1 mg/l, which is significantly less than a therapeutic dose.

What foods contain theophylline?

Theophylline is found in black tea and to a lesser extent in green coffee, cocoa cotyledon and dried mate.

What kind of drug is theophylline?

Theophylline is used to treat lung diseases such as asthma and COPD (bronchitis, emphysema). It must be used regularly to prevent wheezing and shortness of breath. This medication belongs to a class of drugs known as xanthines.

How quickly does theophylline work?

This medication may be used alone or with an inhaled bronchodilator. How fast does this medication work? This medication works within 30 minutes.

How does theophylline work in the body?

Theophylline works by opening the airways in your lungs. It does this by relaxing the muscles and decreasing the response to substances that cause your airways to constrict. This makes it easier for you to breathe.

What is the generic name for theophylline?

Theophylline (Elixophyllin, Uniphyl): Side Effects, Dosages, Treatment, Interactions, Warnings.

Does green tea contain theophylline?

Black tea, green tea, and oolong tea are all made from the same plant but are prepared using different processing methods. Green tea extract contains polyphenols. … Other significant parts of tea include caffeine, theobromine, and theophylline. The polyphenols of green tea are strong antioxidants.

Does coffee interact with theophylline?

theophylline caffeine Avoid drinks or foods that contain caffeine, such as coffee, tea, cola, and chocolate. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs.

Is theophylline a stimulant?

Theophylline is a drug derived from methylxanthine (a purine derivative) and has smooth muscle relaxant, bronchial dilation, diuretic, cardiac and central nervous system (CNS) stimulant activities.

How long should I take theophylline?

How often do you need to take theophylline? If you’re given theophylline to help manage your asthma every day, it needs to be taken regularly – usually every 12 hours, as prescribed by your doctor. It is very important that you take this medicine exactly as it’s prescribed.

Is theophylline used for COPD?

Theophylline has been used as a bronchodilator in the treatment of COPD for over 70 years, but has lost popularity as better tolerated and more effective bronchodilators have been introduced.

Can you buy theophylline over the counter?

Currently available nonprescription active ingredients are ephedrine–with or without guaifenesin–and epinephrine. Theophylline and phenobarbital previously were active ingredients in nonprescription asthma products; however, both are now classified as prescription-only products.

Does theophylline lower blood pressure?

Both theophylline and enprofylline lowered forearm arterial resistance without an increase in CI, LVEF, or cardiac inotropy, although enprofylline tended to cause a lower blood pressure and higher HR than did theophylline.